In the case mentioned, it is considered respectful to keep the Holy Quran on the top shelf of the wardrobe or in another elevated place. However, if there is no other place to keep the Holy Quran, and due to keep it on the top shelf,there is no alternative for storing clothes, then it is permissible to keep it in the middle shelf.
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دلائل:
الفتاوى الهندية: (324/5، ط: دار الفكر)
حانوت أو تابوت فيه كتب فالأدب أن لا يضع الثياب فوقه.
واللّٰه تعالٰی اعلم بالصواب
دارالافتاء الاخلاص،کراچی